Computer Simulations in the Pharmaceutical Industry: Volume 1 (Drugs and the Pharmaceutical Sciences)

The application of computational modeling and simulation has extended beyond PK/PD prediction of clinical trial outcomes, by defining regulatory strategy as well as optimization of therapeutic candidates.Further, regulatory agencies are accepting modeling and simulations for approval in special populations, drug-drug interactions, and dosing regimen changes.This volume provides a comprehensive coverage of drug design, chemoinformatics, molecular modeling, and computer-aided formulation development.Computer simulations play a crucial role in the pharmaceutical industry, accelerating drug discovery and development by predicting drug behavior, optimizing systems, so reducing the need for animal testing. Key FeaturesIllustrates how computer simulations play a crucial role in the pharmaceutical industry, accelerating drug discovery and development. PK/PD simulations play a crucial role in optimizing dosing regimens and understanding the time course of drug effects. Depicts the role of compu