Global and African Perspectives on Lung Cancer: Integrating Infections, Genomics, and the Exposome (Integrative Cancer Biology and Health Equity)

This book provides a comprehensive and integrated view of lung cancer, combining global evidence with African-specific perspectives.It examines the epidemiology, histological subtypes, and multifactorial causes of the disease, with in-depth coverage of genomic alterations, molecular signatures, and population-specific variations in Africa.The chapters explore the combined impact of environmental exposures, tobacco smoke, air pollution, asbestos, silica, radon, and indoor pollutants and infectious agents, including viruses, bacteria, and parasites, as drivers of lung carcinogenesis.The volume also addresses the role of the exposome, chronic infections, immune modulation, and the lung microbiome in shaping disease risk, treatment response, and survival outcomes.The book also presents the advances in molecular diagnostics, biomarker discovery, precision oncology, and AI-enabled healthcare innovations alongside the influence of social determinants such as poverty, education, cultural facto