Laboratory Assessments of Pediatric Leukemia

Leukemia is the most common childhood cancer, representing about 25% of pediatric malignancies.Survival rates have improved dramatically, especially in cases of acute lymphoblastic leukemia, where personalized, laboratory-guided treatments now achieve cure rates near 90%. Because diagnosis, risk assessment, treatment selection, and monitoring all rely heavily on specialized laboratory testing-and because these technologies continue to evolve-there is a strong need for a comprehensive reference in this field.This book is written to fulfil that need. The text provides an up-to-date overview of laboratory assessments in pediatric leukemia across 21 chapters.Chapter 1 reviews disease classification, diagnosis, and treatment, highlighting the essential roles of laboratory evaluation.Chapters 2-12 cover a wide range of diagnostic and monitoring tests, from basic blood counts to advanced molecular techniques such as long-read sequencing.Chapters 13-15 explore prognostic and predictive biomark